The “monograph on tablets” in Ph. Eur. stipulates that the fragments of scored tablets must comply with either the mass uniformity test or the content uniformity test.

Breakability tests on tablets with “conventional” scoring frequently show that the tablet unintentionally breaks beside the score; the probable cause of this is that the substance is more compacted along the score line, causing higher resistance to breakage.

Divisibility can be improved by changing the design of the score. The “debossed lancet-shaped” score proved to be effective (example c), as did adding extra “band scores” (example d).

The following overview depicts some of the possible score designs.

We can draft tablet drawings incorporating your ideas for score designs, which we then place at your disposal; we would also be delighted to advise you..